American Cruise Lines is the only major river cruise line sailing exclusively U.S. waterways — under the American flag, with American crews, on the rivers that shaped this nation. From the legendary Mississippi to the Columbia-Snake, the Hudson, and the historic rivers of New England, American Cruise Lines delivers an intimate small-ship experience for up to 190 guests. Browse 2026–2028 sailings at guaranteed lowest prices, or call a specialist at 1-800-528-9300.
| Nights | Cruise | Departure | Ship | Starting From | |
|---|---|---|---|---|---|
| 7 | Mississippi | Jul 1 – Jul 8, 2026 | American Splendor | Starting from $4,295 per person, double occupancy · Standard Waterview | Get Discounted Price → |
| 7 | New England | Jul 1 – Jul 8, 2026 | American Star | Starting from $5,240 per person, double occupancy · Standard Waterview | Get Discounted Price → |
| 7 | Mississippi | Jul 1 – Jul 8, 2026 | American Symphony | Starting from $5,275 per person, double occupancy · Standard Balcony | Get Discounted Price → |
| 7 | Columbia & Snake Rivers | Jul 1 – Jul 8, 2026 | American Song | Starting from $6,860 per person, double occupancy · Standard Balcony 2 | Get Discounted Price → |
| 7 | National Parks & Legendary Rivers | Jul 1 – Jul 8, 2026 | American Song | Starting from $14,060 per person, double occupancy · Standard Balcony 2 | Get Discounted Price → |
| 7 | New England | Jul 2 – Jul 9, 2026 | American Legend | Starting from $7,415 per person, double occupancy · Premium Balcony | Get Discounted Price → |
| 7 | New England | Jul 2 – Jul 9, 2026 | American Maverick | Starting from $7,415 per person, double occupancy · Premium Balcony | Get Discounted Price → |
| 7 | Lake Michigan & Upper Peninsula | Jul 2 – Jul 9, 2026 | American Patriot | Starting from $8,675 per person, double occupancy · Premium Balcony | Get Discounted Price → |
| 7 | Ohio River | Jul 3 – Jul 10, 2026 | American Heritage | Starting from $4,610 per person, double occupancy · Standard Waterview | Get Discounted Price → |
| 7 | Mississippi | Jul 4 – Jul 11, 2026 | American Serenade | Starting from $5,635 per person, double occupancy · Standard Balcony | Get Discounted Price → |
| 7 | Puget Sound & San Juan Islands | Jul 4 – Jul 11, 2026 | American Spirit | Starting from $6,290 per person, double occupancy · Standard Waterview | Get Discounted Price → |
| 7 | Columbia & Snake Rivers | Jul 4 – Jul 11, 2026 | American Harmony | Starting from $7,195 per person, double occupancy · Standard Balcony | Get Discounted Price → |
| 7 | Columbia & Snake Rivers | Jul 4 – Jul 11, 2026 | American Harmony | Starting from $14,395 per person, double occupancy · Standard Balcony | Get Discounted Price → |
| 7 | National Parks & Legendary Rivers | Jul 4 – Jul 11, 2026 | American Jazz | Starting from $14,690 per person, double occupancy · Deluxe Balcony 2 | Get Discounted Price → |
| 7 | New England | Jul 5 – Jul 12, 2026 | American Liberty | Starting from $7,415 per person, double occupancy · Premium Balcony | Get Discounted Price → |
| 10 | Alaska | Jul 5 – Jul 15, 2026 | American Constellation | Starting from $9,275 per person, double occupancy · Deluxe Waterview | Get Discounted Price → |
| 14 | New England | Jul 5 – Jul 19, 2026 | American Pioneer | Starting from $13,940 per person, double occupancy · Premium Balcony | Get Discounted Price → |
| 7 | Columbia & Snake Rivers | Jul 6 – Jul 13, 2026 | American West | Starting from $5,555 per person, double occupancy · Standard Waterview | Get Discounted Price → |
| 7 | Columbia & Snake Rivers | Jul 6 – Jul 13, 2026 | American Pride | Starting from $5,870 per person, double occupancy · Standard Waterview | Get Discounted Price → |
| 7 | New England | Jul 6 – Jul 13, 2026 | American Glory | Starting from $6,350 per person, double occupancy · Premium Waterview | Get Discounted Price → |
Prices listed are subject to change, based on availability, and are per person based on double occupancy.
American Cruise Lines offers an experience found nowhere else: America’s rivers, American ships, American crews. Pavlus gets you the best price.
Our high-volume partnership with American Cruise Lines means exclusive savings unavailable when booking direct or through other agencies.
Our advisors have personally sailed with American Cruise Lines. We match you to the right itinerary for your travel style and budget.
Find the same sailing cheaper anywhere? We’ll match it — and often add a Pavlus exclusive amenity on top.
No service fees, no booking fees — ever. Every dollar you spend goes toward your river cruise experience.