American Cruise Lines is the only major river cruise line sailing exclusively U.S. waterways — under the American flag, with American crews, on the rivers that shaped this nation. From the legendary Mississippi to the Columbia-Snake, the Hudson, and the historic rivers of New England, American Cruise Lines delivers an intimate small-ship experience for up to 190 guests. Browse 2026–2028 sailings at guaranteed lowest prices, or call a specialist at 1-800-528-9300.
Questions before you book? American Cruise Lines FAQs → — cabins, what’s included, excursions & how the Pavlus discount works.
| Nights | Cruise | Departure | Ship | American Cruise Lines Price | Pavlus Discounted Price |
|---|---|---|---|---|---|
| 7 | Puget Sound & Northwest | Oct 11 – Oct 18, 2026 | American Constitution | American Cruise Lines Price $6,075 per person, double occupancy · Deluxe Waterview | Get Our Discounted Price → |
| 7 | New England & East Coast | Oct 11 – Oct 18, 2026 | American Pioneer | American Cruise Lines Price $7,835 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | New England & East Coast | Oct 11 – Oct 18, 2026 | American Liberty | American Cruise Lines Price $8,395 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Oct 12 – Oct 19, 2026 | American West | American Cruise Lines Price $5,555 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Oct 12 – Oct 19, 2026 | American Pride | American Cruise Lines Price $5,870 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Hudson River | Oct 12 – Oct 19, 2026 | American Glory | American Cruise Lines Price $7,190 per person, double occupancy · Premium Waterview | Get Our Discounted Price → |
| 7 | Great Lakes | Oct 12 – Oct 19, 2026 | American Patriot | American Cruise Lines Price $8,395 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 6 | Mississippi River | Oct 13 – Oct 19, 2026 | American Heritage | American Cruise Lines Price $3,990 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Puget Sound & Northwest | Oct 13 – Oct 20, 2026 | American Constellation | American Cruise Lines Price $5,675 per person, double occupancy · Deluxe Waterview | Get Our Discounted Price → |
| 7 | Hudson River | Oct 13 – Oct 20, 2026 | American Eagle | American Cruise Lines Price $7,190 per person, double occupancy · Premium Waterview | Get Our Discounted Price → |
| 7 | Ohio & Tennessee Rivers | Oct 14 – Oct 21, 2026 | American Splendor | American Cruise Lines Price $4,925 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Mississippi River | Oct 14 – Oct 21, 2026 | American Symphony | American Cruise Lines Price $5,635 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Oct 14 – Oct 21, 2026 | American Song | American Cruise Lines Price $6,860 per person, double occupancy · Standard Balcony 2 | Get Our Discounted Price → |
| 7 | Ohio & Tennessee Rivers | Oct 14 – Oct 21, 2026 | American Splendor | American Cruise Lines Price $7,425 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Oct 14 – Oct 21, 2026 | American Encore | American Cruise Lines Price $7,920 per person, double occupancy · Deluxe Balcony | Get Our Discounted Price → |
| 7 | Mississippi River | Oct 14 – Oct 21, 2026 | American Symphony | American Cruise Lines Price $8,135 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Southeast & Florida | Oct 16 – Oct 23, 2026 | American Independence | American Cruise Lines Price $4,925 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Mississippi River | Oct 16 – Oct 23, 2026 | American Serenade | American Cruise Lines Price $5,275 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | New England & East Coast | Oct 16 – Oct 23, 2026 | American Legend | American Cruise Lines Price $8,395 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 10 | New England & East Coast | Oct 17 – Oct 27, 2026 | American Star | American Cruise Lines Price $6,290 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
Prices listed are subject to change, based on availability, and are per person based on double occupancy. Instant Savings is either in the form of a discount, Pavlus Cash Back sent closer to Departure, or Onboard Credit depending on the cruise line.
American Cruise Lines offers an experience found nowhere else: America’s rivers, American ships, American crews. Pavlus gets you the best price.
Our high-volume partnership with American Cruise Lines means exclusive savings unavailable when booking direct or through other agencies.
Our advisors have personally sailed with American Cruise Lines. We match you to the right itinerary for your travel style and budget.
Find the same sailing cheaper anywhere? We’ll match it — and often add a Pavlus exclusive amenity on top.
No service fees, no booking fees — ever. Every dollar you spend goes toward your river cruise experience.
*Cash back is calculated on the net fare, which is the fare remaining after travel agency commission is deducted, not on the total booking price. Cash back will therefore be less than 10% of your total. See full terms here.