American Cruise Lines is the only major river cruise line sailing exclusively U.S. waterways — under the American flag, with American crews, on the rivers that shaped this nation. From the legendary Mississippi to the Columbia-Snake, the Hudson, and the historic rivers of New England, American Cruise Lines delivers an intimate small-ship experience for up to 190 guests. Browse 2026–2028 sailings at guaranteed lowest prices, or call a specialist at 1-800-528-9300.
| Nights | Cruise | Departure | Ship | American Cruise Lines Price | Pavlus Discounted Price |
|---|---|---|---|---|---|
| 7 | Columbia & Snake Rivers | Sep 21 – Sep 28, 2026 | American West | American Cruise Lines Price $5,870 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Sep 21 – Sep 28, 2026 | American Pride | American Cruise Lines Price $6,290 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | New England & East Coast | Sep 21 – Sep 28, 2026 | American Glory | American Cruise Lines Price $7,190 per person, double occupancy · Premium Waterview | Get Our Discounted Price → |
| 7 | New England & East Coast | Sep 22 – Sep 29, 2026 | American Independence | American Cruise Lines Price $5,870 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | New England & East Coast | Sep 22 – Sep 29, 2026 | American Eagle | American Cruise Lines Price $7,190 per person, double occupancy · Premium Waterview | Get Our Discounted Price → |
| 7 | Mississippi River | Sep 23 – Sep 30, 2026 | American Splendor | American Cruise Lines Price $4,610 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Ohio & Tennessee Rivers | Sep 23 – Sep 30, 2026 | American Symphony | American Cruise Lines Price $5,275 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | New England & East Coast | Sep 23 – Sep 30, 2026 | American Star | American Cruise Lines Price $5,870 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Sep 23 – Sep 30, 2026 | American Song | American Cruise Lines Price $7,085 per person, double occupancy · Standard Balcony 2 | Get Our Discounted Price → |
| 7 | Ohio & Tennessee Rivers | Sep 23 – Sep 30, 2026 | American Symphony | American Cruise Lines Price $7,775 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Mississippi River | Sep 23 – Sep 30, 2026 | American Splendor | American Cruise Lines Price $7,775 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Sep 23 – Sep 30, 2026 | American Encore | American Cruise Lines Price $7,920 per person, double occupancy · Deluxe Balcony | Get Our Discounted Price → |
| 12 | Great Lakes | Sep 23 – Oct 5, 2026 | American Patriot | American Cruise Lines Price $14,270 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | New England & East Coast | Sep 25 – Oct 2, 2026 | American Legend | American Cruise Lines Price $8,395 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
| 7 | Mississippi River | Sep 26 – Oct 3, 2026 | American Heritage | American Cruise Lines Price $4,925 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Mississippi River | Sep 26 – Oct 3, 2026 | American Melody | American Cruise Lines Price $5,635 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Puget Sound & Northwest | Sep 26 – Oct 3, 2026 | American Spirit | American Cruise Lines Price $6,290 per person, double occupancy · Standard Waterview | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Sep 26 – Oct 3, 2026 | American Jazz | American Cruise Lines Price $7,435 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Columbia & Snake Rivers | Sep 26 – Oct 3, 2026 | American Harmony | American Cruise Lines Price $7,435 per person, double occupancy · Standard Balcony | Get Our Discounted Price → |
| 7 | Hudson River | Sep 26 – Oct 3, 2026 | American Ranger | American Cruise Lines Price $8,395 per person, double occupancy · Premium Balcony | Get Our Discounted Price → |
Prices listed are subject to change, based on availability, and are per person based on double occupancy.
American Cruise Lines offers an experience found nowhere else: America’s rivers, American ships, American crews. Pavlus gets you the best price.
Our high-volume partnership with American Cruise Lines means exclusive savings unavailable when booking direct or through other agencies.
Our advisors have personally sailed with American Cruise Lines. We match you to the right itinerary for your travel style and budget.
Find the same sailing cheaper anywhere? We’ll match it — and often add a Pavlus exclusive amenity on top.
No service fees, no booking fees — ever. Every dollar you spend goes toward your river cruise experience.